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D Secondary cardiovascular compromise

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 Common in horses presented for anesthesia.

 Causes include circulatory shock (e.g. severe hemorrhage), sepsis (e.g. colic) and profound electrolyte imbalance (e.g. uroabdomen in foals).

 Cardiovascular changes that occur in sepsis include:Decreased cardiac output resulting from a direct decrease in cardiac contractility and a decrease in preload due to splanchnic pooling and vascular leakage.Pulmonary hypertension (with subsequent hypoxemia).Complex alterations in systemic BP (initial hypertension followed by hypotension with loss of vascular tone).Drastic alterations in hematologic function, including hypercoagulability followed by hypocoagulability.

Manual of Equine Anesthesia and Analgesia

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