Читать книгу Farm Animal Anesthesia - Группа авторов - Страница 25

Acepromazine is not an effective tranquilizer in pigs, for though tranquilized, they can still resist and fight the imposing restraint viciously. The doses of acepromazine recommended for pigs are 0.11–0.44 mg/kg IV or IM with a maximum total dose of 15 mg [8]. Large doses of acepromazine have been administered in addition to local anesthesia to sows undergoing cesarean section surgery, resulting in severe hypotensive shock. Several sows did not recover following the surgery [14]. IM doses of 0.05–0.5 mg/kg have been given to Vietnamese potbellied pigs with an unreliable calming effect even with high doses [15]. Acepromazine is frequently used in combination with ketamine or Telazol (tiletamine/zolazepam) to produce excellent sedation and muscle relaxation [16]. In pigs susceptible to malignant hyperthermia, acepromazine at 1.1 and 1.65 mg/kg IM has been reported to reduce the incidence of malignant hyperthermia by 40% and 73%, respectively. A lower dose of 0.55 mg/kg IM only delayed but did not prevent the onset of the episode [17].