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2.3.3 Swine 2.3.3.1 Xylazine

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Compared to other domestic species, pigs are the least sensitive to xylazine. A higher dose (1.65 mg/kg IV, 2.2 mg/kg IM) is required to produce mild to moderate sedation, but still the pigs are easily aroused and able to flee when approached [8, 14]. Vomiting and bloating have been observed in pigs that were not fasted prior to anesthesia [16, 21]. When tested at doses of 1, 2, 4, 8, and 16 mg/kg IV in young pigs, xylazine alone did not produce effective sedation and analgesia. Xylazine induced a significant decrease in mean arterial blood pressure, but it gradually returned to baseline values 10 minutes after administration [102].

Farm Animal Anesthesia

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