Читать книгу Transfusion Medicine - Jeffrey McCullough - Страница 100

The selection of donors for plateletpheresis, leukapheresis, and plasmapheresis uses the same general criteria used for whole blood donors [1]. Because of the unique nature of apheresis, there are some additional donor requirements that are based on the unique complications that may occur from apheresis, the nature of the procedures, and the fact that because few red cells are removed, donors can undergo cytapheresis more often than whole blood donation. The amount of blood components removed from apheresis donors must be monitored. To be consistent with whole blood donation, not more than 200 mL of red cells may be removed in 8 weeks. If for some reason, such as instrument failure, it is not possible to return the red cells to the donor, then the donation is treated as if it were a whole blood donation, and the donor cannot donate again for 8 weeks. For consistency with plasma donation, not more than 1,000–1,200 mL of plasma per week may be retained. When donors undergo apheresis more often than every 8 weeks, this is referred to as “serial” donation, and cumulative records must be maintained of the details of these donations, and the records must be reviewed periodically to assure that requirements related to red blood cells and plasma are met. The laboratory testing of donors and apheresis components for nonbacterial pathogens is essentially the same as for whole blood donation. Thus, the likelihood of disease transmission from apheresis components is similar to whole blood components.