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Allogeneic donors for hematopoietic cell transplantation

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Hematopoietic cell transplantation now uses a variety of donors, such as unrelated marrow, peripheral blood stem cells (PBSCs), or cord blood. Transfusion medicine physicians are involved in this donor selection process. The criteria for whole blood and apheresis donation serve as the basis for donor selection, but these criteria may be modified because the advantage of a particular donor may outweigh a very small or theoretical increased risk of the cellular product. Criteria intended to protect the donor are less likely to be modified, but as new donation situations, such an unrelated marrow or cord blood, have arisen, donor selection criteria for each situation were developed.

Transfusion Medicine

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