Читать книгу Transfusion Medicine - Jeffrey McCullough - Страница 95

Although most reactions are mild, severe reactions defined as those requiring hospitalization can occur. These include seizures, myocardial infarction, tetany, and death. Popovsky [57] reviewed 4,100,000 blood donations and found very severe reactions in 0.0005%, or 1 per 198,110 allogeneic blood donations. The kinds of reaction included severe vasovagal reaction, angina, tetany, and problems related to the venipuncture site. Most reactions occurred during donation while the donor was at the donor site, although 6% occurred more than 3 days later. Reactions were more likely in first‐time donors. If this incidence is generalized to the total yearly donations of 15 million, approximately 75 such reactions may occur annually.