Читать книгу Large Animal Neurology - Joe Mayhew - Страница 84

Proliferated Schwann cells mainly guide and ensheath regrowing axons during the process of Wallerian regeneration in the PNS. Thus, following focal or diffuse PNS axonal lesions, such proliferation is evident. Schwann cells, like oligodendrocytes, are subject to immune and toxic attack and are sometimes affected by inherent metabolic disorders. This may occur before or after normal developmental myelination, causing hypomyelination or demyelination, respectively. Unlike oligodendrocytes, Schwann cells are quite efficient at recoating bare PNS axons and repairing lesions. They do not appear to contribute to the often impressive Renaut body formation in peripheral nerves (Figure 4.6).