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Neuropathologic responses in the various mechanisms of disease

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Interpretation of neurohistopathologic sections and reports can be made with consultation of current reference books2,6 and especially e‐libraries such as the Cornell University Atlas of Veterinary Neuropathology27 and others.28,29

Just as each mechanism of disease has its own clinical characteristics as outlined in Chapter 2, so each has certain morphologic characteristics. Thus, one must understand that vascular disorders result in abrupt, localized hypoxia and tissue necrosis, as well as the leakage of blood protein and pigments. This is as clinically relevant as understanding that such diseases usually have a sudden onset of signs that remain static or, more frequently, improve with time: consider fibrocartilaginous emboli in pigs and equine herpesvirus myeloencephalopathy.

Large Animal Neurology

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