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Neurotransmitters of Wakefulness and Sleep

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The role of neurotransmitters in both the sleep as well as the wake state is a complex topic that is becoming better understood and recognized. A specific set of neurotransmitters play a role in either the sleep or the wake state. Accordingly, sleep is no longer viewed as an alternative to being awake but is actually an active neurobehavioral state that is governed by the central nervous system. No one substance acts alone. A complex interaction of these is responsible to maintain the states of wakefulness and sleep. Based on a variety of detailed references, the significant aspects of the neurotransmitters are reviewed [5, 23–26] (Table 2.2).

Dental Management of Sleep Disorders

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