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Norepinephrine (NE)

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NE, also known as noradrenalin, maintains EEG activity, has reduced activity during NREM sleep, and has near complete loss of activity during REM. NE is most active in the wake state, is released by the LC, and is associated with an increase related to attention and activity that impacts the sympathetic nervous system [30]. NE may have an effect on orexin as it relates to arousal [23].

Dental Management of Sleep Disorders

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