Читать книгу Dental Management of Sleep Disorders - Ronald Attanasio - Страница 39

5HT was initially known to be involved with sleep. At this time, it is known to modulate the sleep and the wake state, as well as the CR. This is associated with the area in the brain and the specific receptors that are impacted [31]. It is well known for a wide variety of functions associated with mood, depression, pain, and of course sleep. It is found to be excitatory and can impact the wake state. 5HT is most active during the wake state, less active in NREM, and has a low level of activity during REM [23].