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SLNs (Figure 1.2e) are among the class of lipid nanoparticles having a size in the range of 1–1000 nm, usually have a crystalline lipid core which is stabilized by interfacial surfactants (Sun et al. 2019). These nanomaterials were introduced in 1991 for the first time. SLN are reported as having various novel properties such as easy synthesis, low cost, ability to store various molecules/drugs with high loading capacity, controlled drug release, improved stability, improved biopharmaceutical performance, etc. Therefore, SLN have been preferably used over the other various drug delivery systems like emulsions, liposomes, and polymeric nanoparticles (Pink et al. 2019).