Читать книгу Nanobiotechnology in Diagnosis, Drug Delivery and Treatment - Группа авторов - Страница 38

Mycobacterium tuberculosis (MTB) is the causative agent for pulmonary tuberculosis causing worldwide deaths. It affects all the parts of the body, but lungs are mostly infected due to inhalation of MTB. Drug dosage for the treatment is generally given orally and repeated doses in high concentration are required for the treatment process. However, drug administration through inhalation is more advantageous and requires lower doses. Encapsulated nanoparticles for drug delivery efficiently penetrate the biological membrane and reach the target site. MSNPs were reported to act as a platform for the delivery of anti‐TB drugs. Functionalized MSNPs could be internalized competently and used as controlled drug delivery vehicles (Singh et al. 2019).