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Dendrimers (Figure 1.2f) are highly branched three‐dimensional nanomaterials consisting of polymeric branching units attached to a central core through covalent bonding, which are organized in concentric layers and that terminate with several external surface functional groups (Lombardo et al. 2019). Dendrimers are synthetic nanomaterials fabricated by a specific synthesis approach involving a series of different reactions that allow precise control on various parameters like size, shape, and surface chemistry which result in highly monodisperse nanostructures. Like various other nanomaterials described above, it is possible to conjugate suitable drugs or macromolecules like proteins or nucleic acid into the surface of dendrimers in order to use them as potential nanocarrier (Virlan et al. 2016). Dendrimers reportedly enhance the solubility and bioavailability of hydrophobic drugs that are entrapped in their intramolecular cavity or conjugated on their surface. However, various factors such as surface modification, ionic strength, pH, temperature, etc., influence the structural properties of dendrimers (Choudhary et al. 2017). Figure 1.2 represents the schematic illustration of various organic nanomaterials.