Читать книгу The Peripheral T-Cell Lymphomas - Группа авторов - Страница 70

 Mouse models of T‐cell lymphomas have been established based on the analysis of mutational profiles or gene/protein expression profiles of human samples.

 Patient‐derived xenograft models of T‐cell lymphomas have been also generated as potential preclinical tools for translational research.

 Mouse models have helped to unveil the pathogenesis and signaling pathways in T‐cell lymphomas.

 Mouse models provide tools to achieve higher rates of successful translation of basic research to clinical trials.