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Advances in Radiation Therapy
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Страница 1
Страница 2
Progress in Tumor Research
Advances in Radiation Therapy
Страница 5
Contents
Preface
References
Страница 9
Principles and Developments in Cancer Immunotherapy and Approaches for Combination with Tumour Irradiation
Abstract
Historical Overview of Immunotherapy Development Cancer Immunotherapy with Induced Erysipelas
Immunological Features in the “Hallmarks of Cancer”
Development of Ipilimumab
Cancer Immunotherapy Concepts Checkpoint Inhibition
Cancer Vaccines
T Cell-Engaging Therapies
Immunocytokines
Other Immunotherapy Strategies
Challenges in Immunotherapy Development
Immunological Effects of Radiation, Rationale for Combination Therapies
Combination Concepts Combination of Irradiation and Immune Checkpoint Inhibition
Antigen Release through Irradiation and Cancer Vaccines
T Cell Effects and T Cell-Engaging Therapy
Tumour Microenvironment and Cytokine-Based Therapies
Combination of Radiotherapy and Immunotherapy in the Clinic Concepts for Clinical Combinations
Questions and Challenges
Conclusion
References
Страница 30
Imageable Biomarkers for Radiotherapy Response
Abstract
PET Imaging
Imageable Biomarkers Imaging of Hypoxia
Hypoxia and Radioresistance
Causes of Hypoxia
Counteracting Hypoxia
PET-Based Hypoxia Imaging
Advantages and Disadvantages of PET-Based Hypoxia Imaging
MRI-Based Hypoxia Imaging
Imaging of Proliferation Proliferation and Radioresistance
Causes of Accelerated Proliferation
Counteracting Radioresistance due to Proliferation
PET-Based Proliferation Imaging
The Future of Biomarker Imaging for Radiotherapy
References
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