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The Alliance of Genome Resources is a consortium of six model organism databases (MODs) and the (GO) consortium. The purpose of the alliance is to provide a central data resource that provides a common user interface to query genomic data and integrates the data from different organisms allowing this data to be viewed in a consistent manner. The Alliance also provides links back to the primary data in many cases. The ability to compare common data across multiple model organisms in an integrated manner is a very useful and powerful tool [23]. The MGD is one of the founding members of the Alliance.

Figure 2.1 Data integration strategy for Monarch. Data, mainly “genotype‐to‐phenotype,” are gathered from a wide range of databases and parsed so that they can be organized into an integrated knowledge graph based on the 35 underlying ontologies used by Monarch describing for example genotype–phenotype relations, diseases, and gene properties. The knowledge graph can then be browsed, searched, or semantic similarity between entities calculated to look for related diseases or mutant strains, for example, where the relationship had previously not been noticed. The databases integrated by Monarch can be found on https://monarchinitiative.org/about/data‐sources.

Source: Image reproduced with permission from Monarch.