Читать книгу Pathology of Genetically Engineered and Other Mutant Mice - Группа авторов - Страница 30

This is another search capability of MGI. It allows researchers to ask how inbred mouse strains differ from each other at the molecular level by enabling queries of SNP data for 88 strains of mice obtained from NCBI's dbSNP resource (Build 142) [35, 36]. Users can query by gene, proximity to gene, and strain and results can be sorted by dbSNP Function Classes or by Strain, and drag columns to reposition strains of interest [37].

Figure 2.2 The Mouse Models of Human Cancer Database (MMHC), formerly Mouse Tumor Biology Database (MTB). Data on frequency and types of cancer in inbred strains and following manipulation (genetically or chemically), photomicrographs, and references are available on this website.

Source: Images were retrieved from the Mouse Models of Human Cancer Database (MMHC, formerly MTB), Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, Maine. World Wide Web (URL: http://tumor.informatics.jax.org) (April 2020).