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Background Strain Comparison Studies Mouse Phenome Database (https://phenome.jax.org)

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The Mouse Phenome Database (MPD) was originally envisioned as a site to host data on comparative studies that utilized multiple inbred strains. It provided a repository for the primary data. As the site evolved, the data could be manipulated to generate a variety of tables to define quantitative differences for specific phenotypes between strains. Today, the site has been refined enabling integration of genomic and phenomic data by providing access to primary experimental data, well‐documented data collection protocols, and a variety of tools to analyze these datasets. Investigators worldwide provided the data on this site which represent a broad scope of disease‐related characteristics in the inbred mouse strains to variations in behavior, morphological, and physiological differences in naive mice and those exposed to drugs, environmental agents, or other manipulations [56].

Pathology of Genetically Engineered and Other Mutant Mice

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