Читать книгу Genomic and Epigenomic Biomarkers of Toxicology and Disease - Группа авторов - Страница 76

Because different miRNAs may have either carcinogenic or antitumor effects, researchers tried to clarify their role in the occurrence and development of MM. In vitro experiments and animal experiments have found that some miRNAs can inhibit tumor growth by regulating cell cycle, proliferation, clone formation, migration, invasion, apoptosis, and other biological processes. Some studies have also shown that miRNAs can directly inhibit the growth of tumors implanted in experimental mice.