Читать книгу Primary Care for COMLEX Level 1 - Dr. Jahan Eftekar - Страница 15
12. SKIN-RELATED CONDITIONS
ОглавлениеPsoriasis
•More in men
•Auspitz
•Spongiform pustule of Kogoj
•Munro’s micro-abscess
•7% of patients with arthritis
•Autosomal dominance
Erythema Multiforme
•Target lesion
•A.K.A. Steven Johnson syndrome
•Recurrence
•“Iris lesion”
Pemphigus Vulgaris
•40-60 years age
•Jewish population
•Intra-epidermal bullae
•Keratinocytes with IgG
•Ethanol Abuse
Bullous Pemphigoid
•60+ age
•Linear IgG in basement membrane
Basal Cell Carcinoma
•Most common skin neoplasm
•Mostly face and scalp
•Pearly border
•Palisading
•Sunlight
Kaposi’s Sarcoma
•More in men
•Children
•Lower extremities with or without visceral involvement
•AIDS
•Purple Plaques
•Spindle cells
•Hemosiderin
Malignant Melanoma
•Horizontal and vertical growth
•Epidermal-dermal junction
•Clark’s level
•Sun exposure
•Most malignant skin neoplasm
•Nodular melanoma
•Metastasis
Acanthosis Nigricans
•Chronic external irritation
•Visceral/internal malignancies
•Hyper-pigmentation
Vitiligo
•Albino-like manifestations
•Antimelanocyte antibodies
Squamous Cell Carcinoma
•Men more than women
•Sun-damaged skin
•Metastatic potency
•Keratin pearls
Herpes Zoster
•Chicken pox
•Dorsal root ganglia
•Dermatome eruption
Albinism
•Tyrosine
•Ocular: X-linked
Contact Dermatitis
•T-cells