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16. ONCOGENIC AGENTS

Оглавление

Viral Oncogens

•HPV ⇔ Cervical carcinoma, 16 and 18

•Kaposi sarcoma associated herpes (KSHV) ⇔ Kaposi’s sarcoma

•EBV ⇔ Burkitt’s Lymphoma, nasopharyngeal carcinoma

•HBV ⇔ Hepatocellular carcinoma

•HTLV-1 ⇔ Adult T-cell leukemia and lymphoma

Energy-Related Oncogens

•UV ⇔ Basal and squamous cell carcinoma + melanoma of skin

•Radiation Therapy ⇔ Leukemias, Thyroid carcinoma, Skin melanoma

Chemical Oncogens

•Viral Chloride ⇔ Hepatic Angiosarcoma

•Thorotrast ⇔ Hepatic angiosarcoma

•Aflatoxin B ⇔ Hepatocellular carcinoma

Other Oncogens

•Alkylating agents ⇔ Leukemia/Lymphoma

•Nitrosamines ⇔ Gastric carcinoma

•Asbestos ⇔ Mesothelioma

•Arsenic ⇔ Squamous cell carcinoma

•Chromium and Nickel ⇔ Pulmonary carcinoma

•Cigarette Smoking ⇔ Pulmonary, Oral and Bladder carcinoma

•Low fiber ⇔ Colon Adenocarcinoma

•High fat ⇔ Breast carcinoma

•Benzene ⇔ Acute leukemia

•Nickel, chromium ⇔ lung cancer

•DES ⇔ Vaginal clear cell Adenocarcinoma, vaginal adenosis

•Alcohol ⇔ Esophageal squamous carcinoma

•N-myc ⇔ Neuroblastoma

•L-myc ⇔ Small cell carcinoma of lung

•Bcl-2 ⇔ Follicular lymphomas

•Erb-b2 ⇔ Breast and ovarian carcinomas

•Myc ⇔ Burkitt’s lymphoma

Primary Care for COMLEX Level 1

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