Читать книгу Primary Care for COMLEX Level 1 - Dr. Jahan Eftekar - Страница 7

Hodgkin’s Lymphoma

•Bilateral hilar Adenopathy

•Young adult men

•Reed-Sternberg Cells (Eosinophilic Giant Cells)

•Stage I-IV

•Elevated erythrocytic sedimentation rate

•Lymphopenia

Non-Hodgkin’s Lymphoma

•B-cells

•Malignancy

•Lymph node adenopathy

•Elevated LDH

•“Starry sky”

•Splenomegaly

Lymphoblastic Lymphoma

•Male children

•Mediastinal mass

•T-cell type

Burkitt’s Lymphoma

•Non-nucleated cells

•High grade B-cell lymphoma

•Starry-Sky histology

•EBV infection

•Translocation Chromosomes 8 and 14

•American form = Abdominal organs, ovary, girls

•African form = jaws, boys

Acute Lymphocytic Leukemia

•Children

•CNS infiltrate

•Ecchymoses

•Lymphoblast

Chronic Lymphocytic Leukemia (CLL)

•B-Cells

•Aged men

•Early hypogammaglobinemia  Granulocytopenia and thrombocytopenia

•Low IgG

Acute Myeloblastic Leukemia (AML)

•Auer rods in myeloblasts

•Adults

•DIC

•Increased PT, PTT

•Splenomegaly

•Translocation 15 and 17

Chronic Myeloid Leukemia (CML)

•Blastic crisis

•Marked leukocytosis

•Middle aged (35-50)

•Myeloid stem cells

•Translocation of 9 and 22 (Philadelphia chromosome)

•No lymphadenopathy

•Splenomegaly

•Ethanol Abuse

Multiple Myeloma

•60+ years

•Normocytic normochromic anemia

•M-protein spike, IgG or IgM

•Urine Bence Jones protein

•Lytic-punched out bony lesions

•Rouleaux formation by RBCs

•Hypercalcemia

•Russell’s bodies

Infectious Mononucleosis

•Rupture of spleen

•Hepatosplenomegaly

•EBV

•Cytotoxic T cells