Читать книгу Bioprospecting of Microorganism-Based Industrial Molecules - Группа авторов - Страница 45
3.6.3 Applications in Nanotechnology
ОглавлениеIn recent years, microbial gums owing to their unique functional properties have been employed in nanotechnology, which has subsequent applications in food and pharmaceutical industries. Various nanostructure has been developed using microbial gums such as nanoparticles, nanofibers, nanocomplexes, and nanoemulsions [50].
A gellan gum containing silver nanoparticle‐based hydrogen sulfide (H2S) biosensor for the detection of meat spoilage was developed. Using this system, H2S was detected in chicken breast, and silver carp; sensor present in the packaging of meats changes color from yellow to white in the presence of H2S. This is a cost‐effective, non‐destructive, and robust method for the detection of meat spoilage [51]. Xanthan gum‐shellac nanoparticles loaded with cinnamon bark extract were assembled by anti‐solvent precipitation method. The nanoencapsulation of the bioactive extract resulted in improved thermal stability and pH resistance having antioxidative properties of the extract [52]. The insulin delivery system triggered by pH was developed using acryloyl cross‐linked dextran dialdehyde (ACDD) nanoparticles to immobilize glucose oxidase. This system works under gastric conditions (pH 1.2), as well as intestinal conditions (pH 7.4) and proved to be a reliable vector for drug delivery [53]. Nanoemulsions made using microbial gums xanthan and welan in combination with Rosemary essential oil were developed. The nanostructure constructed was less than 150 nm in diameter and showed the best physical stability at 0.4% gum concentration with welan gum containing nanoemulsions showing better properties [43].