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Matrix metalloproteinases (MMPs) belong to the family of endopeptidases whose function is to maintain the proteinaceous content of the extracellular matrix in the connective tissues. In the skin, MMPs degrade the excessive matrix collagen, thereby maintaining the flexibility of the skin [26]. Aged cells are found to produce suboptimal levels of MMPs, which enhances the collagen degradation in aging skin. Elevated ROS levels are also known to increase MMPs expression, thereby enhancing skin damage [19, 25].